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large granular lymphocytic leukemia : ウィキペディア英語版 | large granular lymphocytic leukemia
Large granular lymphocytic (LGL) leukemia is a chronic lymphoproliferative disorder that exhibits an unexplained, chronic (> 6 months) elevation in large granular lymphocytes (LGLs) in the peripheral blood. It is divided in two main categoires: T-cell LGL (T-LGL) leukemia and natural-killer (NK)-cell LGL (NK-LGL) leukemia. As the name suggests, ''T-cell large granular lymphocyte leukemia'' is characterized by involvement of cytotoxic-T cells). It is also known by the following terms: ''proliferation of large granular lymphocytes'' (LGLs), ''LGL leukemia'', ''Tγ-lymphoproliferative disorder'', and, in common with other T cell leukemias such as T-cell prolymphocytic leukemia, ''T-cell chronic lymphocytic leukemia''.〔 ==Epidemiology== T-LGL is a rare form of leukemia, comprising 2-3% of all cases of chronic lymphoproliferative disorders.
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